Bioinformatics

Fisher’s Exact Test

Gene Set Enrichment Analysis (GSEA) is a computational method that determines whether an a priori defined set of genes shows statistically significant, concordant differences between two biological states (e.g. phenotypes).

GWAS works backwards in relationship on how pathophysiology is discovered. Given a big dataset of genes, we could do a cross-section of mutations and see the SNPs present in patients with a disease, study the mutations and determine if it’s protective or a risk factor for a disease.

Biopython Is a collection of Python tools for bioinformatics and computational biology. Is part of the “Bio” projects. Features Sequencing Sequence annotation Input and output Accessing online databases Phylogeny Genome diagrams Macromolecular structure Population genetics Wrappers for command line tools